Posted by Archaism on November 02, 2005 at 09:05:21:
In Reply to: Antelope to Antipope posted by Novus Ordo Missae on November 02, 2005 at 08:53:35:
Oseltamivir is an antiviral drug, a neuraminidase inhibitor used in the treatment and prophylaxis of both influenza A and influenza B. Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It was developed by Gilead Sciences and is currently marketed by Hoffman-La Roche (Roche) under the trade name TamifluŽ.
Oseltamivir is a prodrug (usually administered as phosphate), it is hydrolysed hepatically to the active metabolite, the free carboxylate of oseltamivir (GS4071).
Like zanamivir, oseltamivir acts as a transition-state analogue inhibitor of influenza neuraminidase.